{"id":712,"date":"2023-06-21T14:25:29","date_gmt":"2023-06-21T05:25:29","guid":{"rendered":"http:\/\/kyunam.com\/?p=712"},"modified":"2023-06-23T14:23:50","modified_gmt":"2023-06-23T05:23:50","slug":"%ec%96%bc%eb%a6%ac%ed%85%8d-%ea%b2%b0%ea%b3%bc-%ec%9c%84%ec%96%91%ec%84%b1false-positive-%ec%86%8c%eb%8f%99-%ed%9b%84%ea%b8%b0","status":"publish","type":"post","link":"http:\/\/kyunam.com\/?p=712","title":{"rendered":"\uc5bc\ub9ac\ud14d \uacb0\uacfc \uc704\uc591\uc131(False-Positive) \uc18c\ub3d9 \ud6c4\uae30"},"content":{"rendered":"\n
\ubcf8 \ud3ec\uc2a4\ud305\uc740 \uc5bc\ub9ac\ud14d\uc758 \uac80\uc0ac \uacb0\uacfc\ub098, \uac80\uc0ac \uc790\uccb4\uc5d0 \uc774\uc288\ub97c \uc81c\uae30 \ud558\uae30 \uc704\ud55c \ud3ec\uc2a4\ud305\uc774 \uc544\ub2d9\ub2c8\ub2e4. \uc5bc\ub9ac\ud14d \uc790\uccb4\uc5d0 \ub300\ud55c \uc815\ubcf4\uac00 \uc778\ud130\ub137 \uc0c1\uc5d0 \ub9ce\uc9c0 \uc54a\uace0, \uc81c\uac00 \uacaa\uc740 \uacbd\ud5d8\uacfc \uadf8 \uacfc\uc815\uc5d0\uc11c \uc624\ud574 \ud560 \uc218 \uc788\ub294 \ubd80\ubd84\ub4e4\uc744 \uc815\ub9ac\ud574\uc11c \uc720\uc0ac\ud55c \uacbd\ud5d8\uc744 \ud558\uc2e0 \ubd84\ub4e4\uc5d0\uac8c \ub3c4\uc6c0\uc744 \uc8fc\uace0\uc790 \ud568\uc785\ub2c8\ub2e4. \ubcf8 \ud3ec\uc2a4\ud305\uc740 \uc778\uc6a9\/\uc7ac\ud65c\uc6a9\/\ubc1c\ucdcc\ub97c \uc77c\uccb4 \ud5c8\uc6a9\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \ub2e8\uc21c \ub9c1\ud06c\ub85c\ub9cc \uc81c\uacf5\ud574\uc8fc\uae30 \ubc14\ub77c\uba70, \ud2b9\ud788 \uc77c\ubd80 \ub0b4\uc6a9\uc744 \ud2b9\uc815 \ubaa9\uc801\uc73c\ub85c \uc0ac\uc6a9\uc740 \uae08\ud569\ub2c8\ub2e4.<\/strong>\n\n\uc800\ub294 \uc758\ud559 \uc804\ubb38\uac00\ub098 \uad00\ub828 \ubd84\uc57c \uc885\uc0ac\uc790\uac00 \uc544\ub2c8\ub2c8 \ub0b4\uc6a9\uc0c1 \uc624\ub958\uac00 \uc788\uc744 \uc218 \uc788\uc74c\uc744 \uac10\uc548\ud574 \uc8fc\uc138\uc694. <\/pre>\n\n\n\n
\ub9cc40\uc138 \uc774\uc0c1 \ud68c\uc0ac\uc6d0\ub4e4\uc5d0\uac8c\ub294 \ubd88\uc548\ud558\uae30\ub3c4 \ud558\uc9c0\ub9cc \uc274 \uc218 \uc788\ub294 \ub0a0\uc774 1\ub144\uc5d0 \ud55c \ubc88 \uc788\ub2e4. \ubc14\ub85c \uc885\ud569\uac74\uac15\uac80\uc9c4!  (\ub144 1\ud68c \uadfc\ub85c\uc790\uc758 \uac74\uac15\uac80\uc9c4\uc740 \ubc95\uc801\uc73c\ub85c \uac15\uc81c\ub41c \ud56d\ubaa9\uc785\ub2c8\ub2e4.) \ub9cc30\uc138\ubd80\ud130\ub294 \uaca9\ub144\uc73c\ub85c \ubc1b\ub294\ub2e4. \ucc98\uc74c\uc5d0\ub294 \ud070 \ubcd1\uc774 \ub098\uc62c\uae4c \uac71\uc815\ub3c4 \ub9ce\uc774 \ub418\uc5c8\uc9c0\ub9cc \uc2dc\uac04\uc774 \uc9c0\ub098\uc790 \uc810\uc810 \uc26c\ub294 \ub0a0\ub85c.. \ucfe8\ub7ed….<\/p>\n\n\n
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Image by Gerd Altmann<\/a> from Pixabay<\/a><\/figcaption><\/figure>\n<\/div>\n\n\n
\uc544\ubb34\ud2bc, \uc62c\ud574\ub3c4 ’23\ub144\ub3c4 \uc885\ud569\uac74\uac15\uac80\uc9c4\uc774 \ucc3e\uc544\uc654\ub2e4. \ucd5c\uadfc \uc774\uc9c1\uc744 \ud558\uba74\uc11c \uc885\ud569\uac74\uac15\uac80\uc9c4 \uc77c\uc815\uc774 \ud2c0\uc5b4\uc84c\uc5b4\uc694. \uc6d0\ub798 2\uc6d4\uc5d0 \ud6c4\ub2e4\ub2e5 \ud588\uc74c. (\uc77c\ucc0d \ud558\uba74 \ucd94\uac00 \uac80\uc9c4\uc774 \uc788\uc5c8\uc74c! @.@) \uc62c\ud574\ub294 \uc870\uae08 \ub2a6\uac8c 6\uc6d4\uc5d0 \ud558\uac8c \ub418\uc5c8\ub124. \uac74\uac15 \uac80\uc9c4 \ud56d\ubaa9 \uc911 \uc62c\ud574 \ucbe4 \ud588\uc5b4\uc57c \ud558\ub294 \ub300\uc7a5 \ub0b4\uc2dc\uacbd\uc774 \uc788\uc74c. \ub300\uc7a5 \ub0b4\uc2dc\uacbd\uc740 \uc120\uc885(\ub300\uc7a5\ub0b4 \uc0dd\uae34 \ud639\uac19\uc740 \uc870\uc9c1\uc73c\ub85c \ubc29\uce58\uc2dc \ub300\uc7a5\uc554\uc73c\ub85c \ubc1c\uc804\ud560 \uc218 \uc788\uc74c)\uc774 \uc804\uc554 \ub2e8\uacc4\uac00 \ub418\ub294 \uac83\uc774 5\ub144 \uc815\ub3c4\uc774\uae30 \ub54c\ubb38\uc5d0 \ucd5c\uc18c 5\ub144 \uc8fc\uae30\ub85c \ubc1b\uc544\uc57c \ud55c\ub2e4 \ud55c\ub2e4. \uc774\ubbf8 \uc774\uc804\uc758 2\ubc88\uc758 \ub300\uc7a5 \ub0b4\uc2dc\uacbd \uacbd\ub825(?)\uc774 \uc788\uc9c0\ub9cc \uc120\ub4ef \ubc1b\uace0 \uc2f6\uc9c0\ub294 \uc54a\uc740 \uac80\uc0ac\uc778\uc9c0\ub77c……<\/p>\n\n\n
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Image by Elias<\/a> from Pixabay<\/a><\/figcaption><\/figure>\n<\/div>\n\n\n
\ub300\uc7a5 \ub0b4\uc2dc\uacbd \uc790\uccb4\ub294 \uc218\uba74(\uc815\ud655\ud788\ub294 \uc758\uc2dd\ud558 \uc9c4\uc815 \ub0b4\uc2dc\uacbd)\uc73c\ub85c \uc9c4\ud589 \ud558\uae30 \ub54c\ubb38\uc5d0 \ud070 \uac70\ubd80\uac10\uc774 \uc5c6\uc9c0\ub9cc  \uc804\ub0a0 \ub610\ub294 \ub2f9\uc77c(\uc624\ud6c4 \uac80\uc9c4) \uc0c8\ubcbd\uc758 \uc7a5\uc138\ucc99 \uacfc\uc815(\uc57d\ubb3c \ubcf5\uc6a9 \ubc0f \uacfc\uc815)\uc774 \uaf64\ub098 \ubd88\ud3b8\ud558\uba70, \uac80\uc0ac 2~3\uc77c \uc804\ubd80\ud130 \uc74c\uc2dd\ubb3c\uc758 \uc885\ub958\ub97c \uc81c\ud55c\ud574\uc57c \ud558\ub294 \uad49\uc7a5\ud788 \ubc88\uc7a1\uc2a4\ub7ec\uc6b4 \uac80\uc0ac\uc774\ub2e4. \ud2b9\ubcc4\ud788 \uc8fc\uc704\ub97c \uc694\uad6c\ud558\ub294 \uac74\uac15 \uc0c1\ud0dc\uac00 \uc544\ub2cc \uc0ac\ub78c\uc740 \ubc88\uc7a1\uc2a4\ub7ec\uc6b0\uba74 \ub05d\uc774\uc9c0\ub9cc \ub2e4\uc591\ud55c \uc774\uc720\ub85c \uc704 \uacfc\uc815\uc774 \uc5b4\ub824\uc6b4 \uc0ac\ub78c\ub3c4 \uc788\ub294 \uac83\ub3c4 \uc0ac\uc2e4\uc774\uace0. \uc544\ubb34\ud2bc \ub300\uc7a5 \ub0b4\uc2dc\uacbd\uc744 \ud558\ub824\uace0 \uc0dd\uac01\ud558\ub2c8 \uac00\uc2b4\uc774 \ub2f5\ub2f5\ud558\ub2e4. \uadf8\ub7f0\ub370 \uc791\ub144\uc5d0 \uc9c4\ud589\ud55c ‘\uc5bc\ub9ac\ud14d \ub300\uc7a5\uc554 \ubcf4\uc870\uc9c4\ub2e8 \uac80\uc0ac’\uac00 \uc0dd\uac01\uc774 \ub098\uc11c \uc9d1\uc73c\ub85c \uc628 \uc7a5\uc138\ucc99 \uc6a9\uc561\uc744 \ubc18\ub0a9\ud558\uace0 \uc5bc\ub9ac\ud14d \uac80\uc0ac\ub85c \ub300\uc2e0 \ud558\uae30\ub85c \ud568. <\/p>\n\n\n\n
\uc774\ub54c\ub294 \ubab0\ub790\uc9c0… \uc5b4\ub5a4 \uc77c\uc774 \ubc8c\uc5b4 \uc9c8\uc9c0… \ub098\uc911\uc5d0 \uacf1\uc539\uc5b4 \ubcf4\ub2c8 \uc9c4\ub2e8\uac80\uc0ac\uc758 \uc774\ub984\uc774 ‘\uc5bc\ub9ac\ud14d \ub300\uc7a5\uc554 \ubcf4\uc870\uc9c4\ub2e8<\/strong> \uac80\uc0ac’ \uc600\ub2e4. \ub300\uc7a5\ub0b4\uc2dc\uacbd\uc758 \ub300\uccb4 \uac80\uc0ac\uac00 \uc544\ub2c8\ub77c \uc120\uc81c\uc801 \uac80\uc0ac\ub77c\ub294 \uc0ac\uc2e4\uc5d0 \ub300\ud574\uc11c \ubd84\uba85\ud788 \uc54c\uc544\uc57c \ud55c\ub2e4. \uc65c \uadf8\ub7f0\uc9c0\ub294 \ucc28\ucc28  <\/p>\n\n\n\n
\uc5bc\ub9ac\ud14d \uac80\uc0ac\ub294 \ub300\uc7a5 \ub0b4\uc2dc\uacbd \ub300\ube44 \uac04\uc18c\ud55c \uc808\ucc28\uc640 \uc801\uc740 \uace0\uc0dd\uc774 \uc7a5\uc810\uc774\uc9c0\ub9cc, \uc77c\ubc18\uc801\uc778 \ucc44\ubcc0 \uac80\uc0ac\uc5d0 \ube44\ud574\uc11c(\uc5bc\ub9ac\ud14d\uc740 \ucc44\ubcc0\uc744 \ud1b5\ud574\uc11c \ubd84\ubcc0\uc73c\ub85c \uac80\uc0ac) \uc0c1\ub2f9\ud788 \ub9ce\uc740 \uc591\uc758 \ubd84\ubcc0\ub7c9\uc744 \uc694\uad6c \ud55c\ub2e4. \uccab \uac80\uc0ac\ub54c \uc0c1\ub2f9\ud788 \ub2f9\ud669\ud588\ub358 \uae30\uc5b5\uc774 \uc78a\ud600\uc9c0\uc9c0… \uc774\ub807\uac8c\ub098 \ub9ce\uc774……<\/p>\n\n\n\n
\uadf8\ub9ac\ud558\uc5ec \ud798\ub4e0 \ucc44\ubcc0 \uacfc\uc815\uc744 \ud1b5\ud574\uc11c \uc81c\ucd9c \ud558\uace0 \uc885\ud569\uac80\uc9c4\uc744 \uc9c4\ud589\ud558\uba74\uc11c  \uc704 \ub0b4\uc2dc\uacbd\uc744 \uc218\uba74\uc73c\ub85c \ud558\uba74\uc11c… \uc544… \ub300\uc7a5 \ub0b4\uc2dc\uacbd \uadf8\ub0e5 \ud560\uac83 \uadf8\ub7ac\ub098? \ub77c\ub294 \ud6c4\ud68c\uac00 \uc788\uc5c8\uc9c0\ub9cc \ub2e8\uc21c\ud788 \ub0b4\uc2dc\uacbd\uc744 \ud558\uace0 \uc548\ud558\uace0\uc758 \ubb38\uc81c\uac00 \uc544\ub2c8\uc600\uc73c\ubbc0\ub85c \uc704\ub85c\ub97c \ud558\uba74\uc11c \uac80\uc9c4\uc744 \ub9c8\ucce4\ub2e4. \uadf8\ub9ac\uace0 2\uc8fc \ud6c4 \uac80\uc0ac \uacb0\uacfc\uac00 \uc9d1\uc5d0 \ub3c4\ucc29\ud558\uc5ec \uc2a5\uc2a5 \uacb0\uacfc\ub97c \uc0b4\ud3b4 \ubcf4\ub294\ub370….<\/p>\n\n\n
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\ud5c9… \uc591\uc131\uc774 \ub098\uc624\ub2e4\ub2c8, \uc774\uac8c \ubb34\uc2a8 \uc77c\uc774\uc57c. \u3160.\u3160 \uacb0\uacfc\uc9c0\ub97c \uba87 \ubc88 \uc529 \uccd0\ub2e4 \ubcf4\uba74\uc11c \ub4f1\uc5d0 \uc2dd\uc740 \ub540\uc774 \uc8fc\ub974\ub975 \ud750\ub974\ub294 \uac83\uc744 \ub290\ub07c\uba70, \ub9e4\uc6b0 \uc554\ub2f4\ud568\uc744 \ub290\ub07c\uc84c\ub2e4. \ud751\ud751. \uadf8\ub7f0\ub370 \uacb0\uacfc\uc9c0\uc758 \uadf8\ub798\ud504\ub97c \ubcf4\ub294\ub370 \uc880 \uc758\uc544 \ud588\uc74c. \uc6b0\uc120 \uc544\ub7ab\ucabd\uc5d0 \uc788\ub294 x\ucd95\uc758 \uc22b\uc790\uac00 \uc758\ubbf8 \ud558\ub294 \uac83\uc774 \ubb34\uc5c7\uc778\uc9c0 \uad81\uae08\ud558\uc600\uace0, \ud310\uc815 \uae30\uc900\uce58\ub97c \ub9c8\uc9c0\ub9c9 \ubd80\ubd84\uc5d0\uc11c \uc0b4\uc9dd \ub118\uc5b4\uc120 \ubd80\ubd84\uc774 \ub9e4\uc6b0 \uc758\uc544\ud588\uc74c. \uadf8\ub798\uc11c \uc791\ub144 \uac80\uc0ac \uacb0\uacfc\uc9c0\ub97c \uaebc\ub0b4\uc11c \ubd24\ub354\ub2c8<\/p>\n\n\n
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\ubb34\uc5b8\uac00 \ube44\uc2b7\ud55c\ub4ef \ub2e4\ub974\uace0, \ub2e4\ub978\ub4ef \ud558\uba74\uc11c \ube44\uc2b7\ud568\uc744 \ub290\uaef4\uc9c0\uc9c0 \uc54a\ub098? \ub300\ubd80\ubd84 \ube44\uc2b7\ud558\uc9c0\ub9cc x\ucd95\uc758 39, 40\uc774 \uae30\uc900\uce58\ub97c \uc0b4\uc9dd(\uc774\ub77c\uace0 \uacc4\uc18d \ub9d0\ud558\uac8c \ub418\ub354\ub77c\uad6c\uc694.) \ub118\uaca8\uc11c \uc591\uc131 \ud310\uc815. \uac00\uc2b4 \ucff5\ucf85 \uac70\ub9bc\uc744 \ub4a4\ub85c \ud558\uace0 \ud3ed\ud48d \uac80\uc0c9\uc744 \uc2dc\uc791\ud588\uace0 \uc5bc\ub9ac\ud14d \uc591\uc131, \uc5bc\ub9ac\ud14d \ud310\uc815 \ub4f1\ub4f1. \uadf8\ub7f0\ub370 \uac80\uc0c9 \uacb0\uacfc\uac00 \uac70\uc758 \uc5c6\ub2e4. \ub300\ubd80\ubd84 \uc5bc\ub9ac\ud14d\uacfc \uad00\ub828\ub41c \ud64d\ubcf4\uc131 \uae30\uc0ac, \ube14\ub85c\uadf8 \uccb4\ud5d8\uae30 \ub4f1\uc774 \ub300\ubd80\ubd84 \uc774\uace0 \ub0b4\uac00 \uc6d0\ud558\ub294 \uc815\ubcf4\ub294 \uac70\uc758 \uc5c6\ub2e4.<\/p>\n\n\n\n
\uadf8 \uc911\uc5d0\uc11c \ucc3e\uc740 \ud55c \uac1c\uc758 \ube14\ub85c\uadf8 \uae00\uc5d0\uc11c\ub294 ‘\uc591\uc131\uc774\uc5c8\uc9c0\ub9cc \ub300\uc7a5 \ub0b4\uc2dc\uacbd \ud558\ub2c8 \ubcc4 \ubb38\uc81c \uc5c6\uc5c8\uc5b4\uc694.’<\/em> \uc600\ub2e4. \uadf8\ub9ac\uace0 \ud55c \ubcd1\uc6d0 \uc0ac\uc774\ud2b8\uc5d0\uc11c \uc5bc\ub9ac\ud14d \uc18c\uac1c\ub97c \ud558\ub294 \ucee8\ud150\uce20\uc5d0\uc11c \uc591\uc131 \uacb0\uacfc \uadf8\ub798\ud504\ub97c \ubcf4\uc5ec\uc8fc\uc5c8\ub294\ub370 x\ucd95\uc758 20 \uc815\ub3c4 \ubd80\uadfc\uc5d0\uc11c \uae09\uaca9\ud788 \ud310\uc815\uae30\uc900\uce58\ub97c \ub6ab\uace0 \uadf8\ub798\ud504 \ubc16\uc73c\ub85c \ub098\uac00 \ubc84\ub838\ub2e4. \uc774 \ub450 \ube14\ub85c\uadf8\ub97c \ubcf4\uba74\uc11c \uc5b4\uca4c\uba74 \uad1c\ucc2e\uc744 \uc218\ub3c4 \uc788\uc9c0 \uc54a\uc744\uae4c \ud558\ub294 \uc0dd\uac01\uc774 \ub4e4\uc5c8\ub2e4\uace0 \uc0dd\uac01\ud558\uc9c0\ub9cc \uc0ac\uc2e4 \uc800\ub54c\ub294 \uba85\ud655\ud55c \ub2f5\uc774 \uc5c6\uc5b4\uc11c \ub9e4\uc6b0 \ub2f5\ub2f5\ud588\uc74c <\/p>\n\n\n\n
\uadf8\ub9ac\uace0 \ub2e4\uc74c\ub0a0… \uac80\uc9c4 \uae30\uad00\uc5d0 \uc804\ud654\ub97c \ud574\uc11c \uc0c1\ub2f4. \uadf8\ub798\ud504\uc758 \ucc1c\ucc1c\ud568\uc744 \ud574\uc18c\ud574\uc904 \uae30\ub300\uac10\uc774 \uc788\uc5c8\uc9c0\ub9cc \uac80\uc9c4 \uae30\uad00\uc5d0\uc11c\ub294 \uc591\/\uc74c\uc131 \uacb0\uacfc\uc5d0 \ub530\ub77c \ucd94\uac00 \ub300\uc7a5 \ub0b4\uc2dc\uacbd \uac80\uc0ac<\/em><\/strong>\ub97c \uc9c4\ud589\ud55c\ub2e4\uace0 \uc548\ub0b4\ud574 \uc8fc\uc2dc\uace0 \ube44\uc6a9\uc740 \ubb34\ub8cc\ub77c\uace0 \ub9d0\uc500\ud574 \uc8fc\uc168\ub2e4. \uc5bc\ub9ac\ud14d \ub300\uc7a5\uc554 \ubcf4\uc870\uc9c4\ub2e8 \uac80\uc0ac\uc758 \uacb0\uacfc\ub294 \ubcd1\uc758 \ud655\uc9c4\uc774 \uc544\ub2cc \ub300\uc7a5 \ub0b4\uc2dc\uacbd \uc9c4\ud589<\/em><\/strong>\uc774\ub77c\ub294 \uc0ac\uc2e4\uc5d0 \uaf64 \ud070 \ud63c\ub780\uc774 \uc788\uc5c8\uc74c. \uadf8\ub9ac\uace0 \uadf8\ub798\ud504 \uacb0\uacfc\uc5d0 \ub300\ud55c \ubb38\uc758\ub97c \uacc4\uc18d \ud588\ub354\ub2c8 \ud574\ub2f9 \uac80\uc9c4 \uae30\uad00\uc744 \ub2f4\ub2f9\ud558\uc2dc\ub294 \uc9c0\ub178\ubbf8\ud2b8\ub9ad(\uc5bc\ub9ac\ud14d\uc740 \uc9c4\ub2e8 \uac80\uc0ac\uc758 \uc0c1\ud488\uba85\uc774\uace0 \ud68c\uc0ac\ub294 \uc9c0\ub178\ubbf8\ud2b8\ub9ad\uc784) \ub2f4\ub2f9\uc790 \ubd84\uc758 \uc5f0\ub77d\ucc98\ub97c \uc54c\ub824 \uc8fc\uc154\uc11c \ud1b5\ud654\ub97c \ud558\uba74\uc11c \uadf8\ub798\ud504 \ubd80\ubd84\uc744 \ubb38\uc758 \ub4dc\ub838\uace0, \uce5c\uc808\ud558\uac8c \uc124\uba85\uc744 \uc798 \ud574\uc8fc\uc168\ub2e4. \ud2b9\ubcc4\ud55c \uae30\ubc00 \uae30\uc220\uc774 \uc544\ub2cc \uadf8\ub798\ud504 \ud574\uc11d\uc778\uc9c0\ub77c \uacf5\uac1c \ud558\uc790\uba74 x\ucd95\uc758 \uc22b\uc790\ub294 \ud14c\uc2a4\ud2b8 \ubc18\ubcf5 \ud68c\uc218\uc774\ub2e4. \uba54\ud2f8\ud654\ub41c \uc2e0\ub370\uce78-2\ub97c \uac80\ucd9c\ud558\uae30 \uc704\ud574\uc11c \uc5ec\ub7ec \ucc98\ub9ac\ub97c \ud574\uc11c \ud55c \ubc88\ub9cc \uac80\ucd9c\ud574 \ubcf4\ub294\uac8c \uc544\ub2c8\ub77c \ubc18\ubcf5\ud558\uba74\uc11c \ub3d9\uc77c\ud55c \ubd84\ubcc0\uc5d0 \ub300\ud574\uc11c 40\ud68c \uce21\uc815\ud55c\ub2e4\uace0 \ud55c\ub2e4. \uadf8\ub9ac\uace0 \uadf8\ub798\ud504 \uacb0\uacfc\uc5d0 \ub300\ud574\uc11c\ub294 \uc758\uc0ac\uac00 \uc544\ub2c8\uc2dc\uae30 \ub54c\ubb38\uc5d0 \ud655\uc815\ud574\uc11c \ub9d0\uc500\ud574 \uc8fc\uc2e4 \uc218\ub294 \uc5c6\uace0, \uc804\uc554 \ub2e8\uacc4\ubcf4\ub2e4\ub294 \uc6a9\uc885\uc758 \uac00\ub2a5\uc131\uc774 \ub192\uc73c\ub098 \uacb0\uacfc\uac00 \uc591\uc131\uc774\uae30 \ub54c\ubb38\uc5d0 \ub300\uc7a5 \ub0b4\uc2dc\uacbd\uc744 \uaf2d \ud574\ubcf4\uc2dc\ub77c\uace0 \ub9d0\uc500\ud574 \uc8fc\uc168\ub2e4. \uc774\ubbf8 3\uc8fc\ub4a4\uc5d0 \ub300\uc7a5 \ub0b4\uc2dc\uacbd\uc774 \uc7a1\ud600 \uc788\uc5b4\uc11c \ub300\uc7a5 \ub0b4\uc2dc\uacbd\uc744 \ud558\uae30\ub85c \ud588\uc9c0\ub9cc, \ubb54\uac00 \ud655\uc2e4\ud568\uc774 \uc5c6\uc73c\ub2c8 \uc870\uae08\uc740 \ub2f5\ub2f5\ud588\uc9c0\ub9cc \uc5b4\uc9f8\ub4e0 \uc5ec\ub7ec \uc815\ud669\uc0c1 \ud070 \ubcd1\uc740 \uc544\ub2d0 \uac83 \uac19\ub2e4\ub294 \uc0dd\uac01\uc774 \ub4e4\uc5c8\ub2e4.<\/p>\n\n\n\n
\uadf8\ub9ac\uace0 3\uc8fc \ud6c4 3\uc77c\uac04\uc758 \uc74c\uc2dd \uc870\uc808\uacfc \uc7a5\uc138\ucc99 \ud6c4 \ub300\uc7a5 \ub0b4\uc2dc\uacbd\uc744 \uc9c4\ud589\ud588\uace0, \ub300\uc7a5 \ub0b4\uc2dc\uacbd \ub05d\ub09c \ub2f9\uc77c \ud070 \uc774\uc0c1 \uc99d\uc0c1 \uc5c6\ub2e4\ub294 \uc774\uc57c\uae30\ub97c \ube44\ubabd\uc0ac\ubabd\uac04\uc5d0 \ub4e4\uc73c\uba70(\ub300\uc7a5 \ub0b4\uc2dc\uacbd\uc740 \uc57d\uc744 \uc880 \uc384\uac8c \uc8fc\uc2dc\ub294 \ub4ef\ud558\ub2e4….) \uc9d1\uc73c\ub85c \uadc0\uac00\ud588\ub2e4. \uc0ac\uc2e4 \uc815\uc2e0\ub3c4 \uc5c6\uace0 \ubb38\uc81c\uac00 \uc788\uc744 \uae4c\ubd10 \ub108\ubb34 \uac71\uc815\ud574\uc11c \ub2f9\uc77c\uc740 \ubb54\uac00 \uc0dd\uac01\uc744 \uc9d1\uc911\ud560 \uaca8\ub97c\uc774 \uc5c6\uc5c8\ub2e4.<\/p>\n\n\n\n
\uadf8\ub9ac\uace0 \uacb0\uacfc\uac00 \ub098\uc654\ub2e4. \uacb0\uacfc\ub294…. \ub450\ub465<\/p>\n\n\n
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\ube44\ubabd\uc0ac\ubabd\uac04\uc5d0 \ub4e4\uc5c8\ub358 \ub300\ub2f5\uc774 \ub9de\uc558\ub2e4. \uc5bc\ub9ac\ud14d \uac80\uc0ac \uacb0\uacfc\ub294 \uc704\uc591\uc131(False-Positive)\uc600\ub2e4. \uc548\ub3c4\uc758 \ud55c\uc228\uacfc \ud568\uaed8 \uadfc 3\uc8fc\uac04\uc758 \ub9c8\uc74c \uc878\uc784\uc744 \uc120\uc0ac \ud574\uc900 \uc774 \uc0ac\ud0dc\ub97c \uc774\ud574\ud558\uace0 \uc2f6\uc5c8\uace0, \uadf8\ub798\uc11c \uc5bc\ub9ac\ud14d\uc758 \ub9e4\uce74\ub2c8\uc998\uc774 \uad81\uae08\ud574 \uc84c\ub2e4. \ud648\ud53c\uc5d0\uc11c \uc774\ub7f0 \uc800\ub7f0 \ub0b4\uc6a9\ub4e4\uc744 \ubcf4\ub2e4\uac00 \uc758\ud559\uacc4\uc5d0 \ubc1c\ud45c \ub418\uc5c8\ub2e4\ub294 \ub0b4\uc6a9\uc744 \ubcf4\uace0 \ub17c\ubb38\uc744 \ucc3e\uc544 \ubcf4\uc558\ub2e4. <\/p>\n\n\n\n
\uc774\uc81c\ubd80\ud130\ub294 \ub17c\ubb38\uc744 \uc77d\uace0 \uc815\ub9ac\ud55c \ub0b4\uc6a9\uc774\ub77c\uc11c \ubcf5\uc7a1\ud55c \ub0b4\uc6a9\uc774 \ud544\uc694 \uc5c6\ub294 \ubd84\ub4e4\uc740 \uac00\uc7a5 \uc544\ub798 \uacb0\ub860\uc73c\ub85c \uc9c1\ud589!<\/p>\n\n\n\n
\uadf8 \ub17c\ubb38\uc740 \ubc14\ub85c ‘Han, Y.D., Oh, T.J., Chung, TH. et al.<\/em> Early detection of colorectal cancer based on presence of methylated syndecan-2 (SDC2<\/em>) in stool DNA. Clin Epigenet<\/em> 11, 51 (2019). https:\/\/doi.org\/10.1186\/s13148-019-0642-0′ \uc774\ub2e4. \ucd1d 585\uba85\uc758 \ub300\uc7a5\uc554 \ud658\uc790, \uc815\uc0c1\uc778\uc744 \ub300\uc0c1\uc73c\ub85c \uc5bc\ub9ac\ud14d\uc758 \uc815\ud655\ub3c4\ub97c \ud14c\uc2a4\ud2b8\ud55c \ub17c\ubb38\uc774\ub2e4. Open Access\uc774\ub2c8 \ud55c \ubc88\uc529 \uc77d\uc5b4 \ubcf4\uc2dc\uae30\ub97c \uad8c\uc7a5\ud569\ub2c8\ub2e4. \uc758\ud559\ub17c\ubb38\uc774\uc9c0\ub9cc \uc2e4\ud5d8 \uc124\uacc4 \ubd80\ubd84\uc774\ub098 \uacb0\uacfc \ud574\uc11d\uc740 \uc218\uce58\uc801\uc778 \ubd80\ubd84\uc774\ub77c \uc77d\uc5b4 \ubcf4\uace0 \ub0b4 \ub098\ub984\uc758 \uacb0\ub860\uc744 \ub0b4\ub838\uc74c<\/p>\n\n\n\n
\uc6b0\uc120 \uc5bc\ub9ac\ud14d\uc758 \ubbfc\uac10\ub3c4(Sensitivity)\ub294 90.2%\uc774\uace0 \ud2b9\uc774\ub3c4(specificity)\ub3c4 \ubbfc\uac10\ub3c4\uc640 \uac19\uc740 90.2%\uc774\ub2e4. \uc5b4\ub5a4 \uc774\uc57c\uae30\ub098\uba74 \ub300\uc7a5\uc554 \ud658\uc790\ub97c \uac80\uc0ac \uacb0\uacfc\ub85c \ub300\uc7a5\uc554\uc774\ub77c\uace0 \ud310\ubcc4\ud558\ub294 \ud655\ub960\uc774 \ubbfc\uac10\ub3c4 \uc774\uace0 1,000\uba85\uc758 \ud658\uc790 \uc911 902\uba85\uc744 \ub300\uc7a5\uc554\uc774 \uc788\ub2e4\uace0 \ud310\ub2e8 \ud55c \uac83\uc785\ub2c8\ub2e4. \uadf8\ub9ac\uace0 \ub300\uc7a5\uc554\uc774 \uc5c6\ub294 \ud658\uc790\ub97c \ub300\uc7a5\uc554\uc774 \uc5c6\ub2e4\uace0 \ud310\ub2e8\ud55c \ud655\ub960\uc774 1,000\uba85\uc758 \ub300\uc0c1\uc790 \uc911 902\uba85 \uc774\uc5c8\ub2e4\ub294 \uac83\uc785\ub2c8\ub2e4. \ub17c\ubb38\uc5d0\uc11c\ub294 \uc99d\uc0c1\uc774 \uc5c6\ub294 \ub300\uc0c1\uc790\ub97c NED – no evidence of disease\ub77c\uace0 \ud638\uce6d \ud569\ub2c8\ub2e4. <\/p>\n\n\n\n
\uadf8\ub7f0\ub370 \uc815\ud655\ud558\uac8c \ud558\uc790\uba74 \uc5bc\ub9ac\ud14d\uc758 \ubbfc\uac10\ub3c4\uc640 \ud2b9\uc774\ub3c4\ub294 \uc815\ud655\ud788 \ub300\uc7a5\uc554 \ud658\uc790\uc5d0 \ub300\ud55c \ud310\ub2e8\uc758 \ubbfc\uac10\ub3c4\uc640 \ud2b9\uc774\ub3c4\uac00 \uc544\ub2c8\ub2e4. \uc815\ud655\ud788\ub294 \ub300\uc7a5\uc554\uc774 \uc788\uc744 \ub54c \ubd84\ubcc0(Stool)\uc5d0\uc11c \uac80\ucd9c\ub418\ub294 \uba54\ud2f8\ud654 \uc2e0\ub370\uce78-2(methylated syndecan-2<\/em>)\uac00 \uc5bc\ub9ac\ud14d \uac80\uc0ac\ub97c \ud1b5\ud574\uc11c \ub300\uc7a5\uc554 \ud658\uc790\uc5d0\uac8c\uc11c \uac80\ucd9c\ub41c \ubbfc\uac10\ub3c4\uac00 90.2%\uc774\uace0 \uc77c\ubc18 \ub300\uc0c1\uc790\uc758 90.2%\uc5d0\uc11c \uac80\ucd9c\uc774 \ub418\uc9c0 \uc54a\ub294\ub2e4\ub294 \uac83\uc785\ub2c8\ub2e4. \uba38\ub9ac\uac00 \ubcf5\uc7a1\ud574\uc9c0\uace0 \uc544\ub4dd\ud574 \uc9d1\ub2c8\ub2e4. \uc774\uac8c \ubb34\uc2a8 \uc18c\ub9ac\uc778\uac00…. <\/p>\n\n\n\n
\uc774 \uc774\uc57c\uae30\ub97c \uc774\ud574\ud558\uae30 \uc704\ud574\uc11c\ub294 \uc5bc\ub9ac\ud14d\uc758 \ub300\uc7a5\uc554 \ubcf4\uc870\uc9c4\ub2e8 \ubc29\ubc95\uc744 \uc774\ud574\ud574\uc57c \ud55c\ub2e4. \uc885\ud569\uac80\uc9c4 \ud55c \ubc88\uc5d0 \uc774\ub7f0 \uacf5\ubd80\ub97c \ud574\uc57c \ud558\ub2e4\ub2c8….\uc9c0\ub9cc \ubb50 \uc0c1\uc2dd\uc744 \uc704\ud574\uc11c \uc55e\uc11c \ub17c\ubb38\uc5d0\uc11c \ubd84\uc11d\ud55c \ucd1d 585\uba85\uc758 \uc784\uc0c1\uc2e4\ud5d8 \ub300\uc0c1\uc790\ub4e4\uc758 \uac80\uccb4\ub97c \uc6b0\uc120 \uac80\uc0ac\ub97c \ud55c\ub2e4. \uc989, \ub77c\ubca8\ub9c1\ub41c \ub370\uc774\ud130\ub85c \ud559\uc2b5\ud558\ub294\uac70\uc784. (\uc8c4\uc1a1\ud569\ub2c8\ub2e4. \ub525\ub7ec\ub2dd \uad00\ub828 \uc77c\uc744 \ud558\ub2e4 \ubcf4\ub2c8… ) \uadf8\ub798\uc11c \ubd84\uc11d\uc744 \ud574 \ubd24\ub354\ub2c8 \ub300\uc7a5\ud55c \ucd08\uae30\ubd80\ud130 \ub9d0\uae30\uae4c\uc9c0\uc758 \ud658\uc790\uc758 \ubd84\ubcc0\uc5d0\uc11c \uba54\ud2f8\ud654 \uc2e0\ub370\uce78-2\uac00 \ub2e4\ub7c9 \uac80\ucd9c \ub41c\ub2e4\ub294 \uc810\uc744 \ubc1c\uacac\ud558\uc600\ub2e4. \uadf8\ub798\uc11c \uba54\ud2f8\ud654 \uc2e0\ub370\uce78-2\uac00 \ub300\uc7a5\uc554\uc744 \ud310\ubcc4\ud560 \uc218 \uc788\ub294 \uc88b\uc740 \ubb3c\uc9c8\uc778 \uac83\uc784! \ube44\uce68\uc2b5 \ub300\uc7a5\uc554 \uac80\ucd9c \ubc29\ubc95\uc5d0\uc11c \uc88b\uc740 \ubb3c\uc9c8\uc778 \uac83\uc740 \ub9de\ub2e4. \uadf8\ub798\ud504\ub97c \uba3c\uc800 \ubcf4\uba74<\/p>\n\n\n
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(Han, Y, 2019) \uc0c9\uc774 \ub4e4\uc5b4\uac04 \ubc15\uc2a4\ub294 \uc9c1\uc811 \ucd94\uac00<\/figcaption><\/figure>\n<\/div>\n\n\n
Fig. 3\uc744 \ubcf4\uba74 \ub300\uc7a5\uc554 0\uae30\ubd80\ud130 4\uae30\uae4c\uc9c0(CRC)\uc5d0\uc11c \uba54\ud2f8\ud654 \uc2e0\ub370\uce78-2\uac00 \ub2e4\ub7c9 \uac80\ucd9c\ub41c \uac83\uc744 \ud655\uc778\ud560 \uc218 \uc788\ub2e4. \ud2b9\ud788 3\uae30\uc5d0\uc11c \ub3c4\ub4dc\ub77c \uc9c0\ub294 \uac83\uc744 \ud655\uc778\ud560 \uc218 \uc788\ub2e4. \uadf8\ub9ac\uace0 HOP(\uc6a9\uc885 \ubc0f \uae30\ud0c0 \uc885\uc591)\uc5d0\uc11c\ub3c4 \uba54\ud2f8\ud654 \uc2e0\ub370\uce78-2\uac00 \uc77c\ubd80 \uac80\ucd9c\ub418\ub294 \uac83\uc744 \uc54c \uc218 \uc788\ub2e4. \uadf8\ub7f0\ub370 \ub208\uc5ec\uaca8 \ubd10\uc57c \ud560 \uc810\uc740 \ub300\uc870\uad70\uc778 \uc77c\ubc18 \ub300\uc0c1\uc790(NED)\uc758 \ubd84\ubcc0\uc5d0\uc11c\ub3c4 \uba54\ud2f8\ud654 \uc2e0\ub370\uce78-2\uac00 \uac80\ucd9c\ub418\ub294 \uac83\uc744 \ud655\uc778\ud560 \uc218 \uc788\ub2e4. \uc6a9\uc885(HOP)\ubcf4\ub2e4 \ub354 \ub9ce\uc740 \uba54\ud2f8\ud654 \uc2e0\ub370\uce78-2\uac00 \uac80\ucd9c\ub418\uc5c8\ub2e4. \ub2e4\ub9cc, \uba54\ud2f8\ud654 \uc815\ub3c4\uac00 \uc6a9\uc885\uc758 \ucd5c\ub300\uce58\uac00 \ub354 \ub192\uc558\ub2e4. \uc758\ud559 \uc6a9\uc5b4\ub97c \uc798 \ubaa8\ub974\uc9c0\ub9cc \ucd94\uce21\ucee8\ub370 \uc120\uc885\uc740 AA – advanced adenomas<\/em> \uc778\ub4ef \ud558\ub2e4. AA \uc5ed\uc2dc \uba54\ud2f8\ud654 \uc2e0\ub370\uce78-2\uac00 \uac80\ucd9c\ub41c\ub2e4. \uc774 \uc5f0\uad6c\uc5d0 \uc788\ub294 \uadf8\ub798\ud504\uc758 \uacb0\ub860\uc740 \uba54\ud2f8\ud654 \uc2e0\ub370\uce78-2\uac00 \uac80\ucd9c\uc774 \ub418\uba74 \ub300\uc7a5\uc554\/\uc6a9\uc885\/\uc120\uc885\uc774 \uc788\uc744 \uac00\ub2a5\uc131\uc774 \ub9e4\uc6b0 \ub192\ub2e4\ub294 \ub73b\uc774\ub2e4.<\/em><\/strong><\/p>\n\n\n\n
\ud558\uc9c0\ub9cc \uc774 \uadf8\ub798\ud504\uc5d0\uc11c \uac1c\uc778\uc801\uc778 \ucd94\uac00 \ud574\uc11d\uc740 \uba54\ud2f8\ud654 \uc2e0\ub370\uce78-2\uac00 \ub300\uc7a5\uc554 \uac80\ucd9c\uc5d0 \uc88b\uc740 \ubb3c\uc9c8\uc740 \ub9de\uc9c0\ub9cc, NED\uc758 \ub178\uc774\uc988\uac00 \uc0dd\uac01\ubcf4\ub2e4 \ud06c\ub2e4\ub294 \uac83\uc774\ub2e4. \uc774 \ubd80\ubd84\uc774 \ubc14\ub85c \uc704\uc591\uc131\uc5d0 \uae30\uc5ec\ud558\ub294 \ubd80\ubd84\uc778 \uac83 \uac19\ub2e4.<\/p>\n\n\n\n
\uc774\uc81c \uba54\ud2f8\ud654 \uc2e0\ub370\uce78-2\uc758 \uc758\ubbf8\ub97c \ud655\uc778\ud588\uc73c\ub2c8 \uba54\ud2f8\ud654 \uc2e0\ub370\uce78-2\uc758 \uac80\ucd9c\uc774 \uc784\uc0c1\ub300\uc0c1\uc790\/\ub300\uc870\uad70\uc5d0\uc11c \uc5bc\ub9c8\ub098 \uc798 \uac80\ucd9c \ub418\ub294\uc9c0\ub97c \ubcf4\uc790.<\/p>\n\n\n
\n
\"\"
(Han, Y, 2019) \uc0c9\uc774 \ub4e4\uc5b4\uac04 \ubc15\uc2a4, \uc678\uacfd\uc120\uc740 \uc9c1\uc811 \ucd94\uac00<\/figcaption><\/figure>\n<\/div>\n\n\n
\uc704\uc758 \uadf8\ub798\ud504\ub294 \ubbfc\uac10\ub3c4\uc640 \ud2b9\uc774\ub3c4 \uadf8\ub798\ud504\uc774\ub2e4. A \uadf8\ub798\ud504\uc5d0\uc11c \uc88c\uc0c1\ub2e8\uc5d0 \ud45c\uc2dc\ud55c \ubd80\ubd84\uc740 ROC\ucee4\ube0c\uc5d0\uc11c \uc704\uc591\uc131\/\uc704\uc74c\uc131\uc5d0 \ud574\ub2f9\ub418\ub294 \ubd80\ubd84\uc774\ub2e4. \ud1b5\uacc4\uc5d0 \ub300\ud574\uc11c \uc798 \ubab0\ub77c\uc11c ROC\ucee4\ube0c\uc5d0\uc11c AUC 0.902\uac00 \uc5b4\ub290 \uc815\ub3c4\uc758 \uc2e0\ub8b0\uc131\uc744 \ubcf4\uc774\ub294\uc9c0\ub294 \ubaa8\ub974\uaca0\uc9c0\ub9cc \uc218\uce58\ud654\ub41c \uc9c0\ud45c\ub294 \uc800\ub807\ub2e4. B \uadf8\ub798\ud504\ub97c \ubcf4\uba74 NED\uc5d0\uc11c\ub3c4 \uba54\ud2f8\ud654 \uc2e0\ub370\uce78-2\uac00 \uac80\ucd9c\ub418\ub294\uac78 \ud655\uc778\ud560 \uc218 \uc788\ub2e4. <\/p>\n\n\n\n
\uc774 \uc774\uc57c\uae30\uac00 \ubb34\uc2a8 \uc774\uc57c\uae30\ub0d0\uba74 \uc5bc\ub9ac\ud14d\uc744 \uc0ac\uc6a9\ud55c \uac80\uc0ac\ubc95\uc73c\ub85c \uc784\uc0c1\uc2e4\ud5d8\uc790\/\ub300\uc870\uad70\uc744 \ub300\uc0c1\uc73c\ub85c \uba54\ud2f8\ud654 \uc2e0\ub370\uce78-2 \uac80\ucd9c \uac80\uc0ac\ub85c \uc784\uc0c1\uc2e4\ud5d8\uc790\ub97c \ub300\uc7a5\uc554\/\uc6a9\uc885\/\uc120\uc885\uc774 \uc788\ub2e4\uace0 \ubd84\ub958 \ud588\uc744 \ub54c\uc758 \uc591\uc131\/\uc74c\uc131\/\uc704\uc591\uc131\/\uc704\uc74c\uc131 \uacb0\uacfc\ub97c \ub098\ud0c0\ub0b8 \uac83\uc774\ub2e4. <\/p>\n\n\n\n
\uc870\uae08 \ub354 \uc0dd\uac01\ud574 \ubcf4\uba74  \ub300\uc7a5\uc554\uacfc \uba54\ud2f8\ud654 \uc2e0\ub370\uce78-2\ub294 \ud544\uc694\uc870\uac74\uc774\uc9c0 \ud544\uc694\ucda9\ubd84\uc870\uac74\uc774 \uc544\ub2d8\uc744 \uc704\uc5d0\uc11c \ud655\uc778\ud588\uc5c8\ub2e4, \uadf8\ub7f0 \ud55c\uacc4\uc810\uc744 \uac10\uc548\ud558\uace0 \uac80\uccb4\ub97c \ud1b5\ud55c \uba54\ud2f8\ud654 \uc2e0\ub370\uce78-2\uac00 \ubc1c\uacac\uacfc \uc99d\uc0c1\uc758 \uc0c1\uad00\uad00\uacc4\ub97c \ubd84\uc11d\ud588\ub2e4\ub294 \uc774\uc57c\uae30 \uc774\ub2e4. \uc591\uc131 \ud310\uc815\uc774 \ub418\uc5c8\ub2e4\uace0 \ubb34\uc870\uac74 \ub300\uc7a5\uc554\uc740 \uc544\ub2c8\ub77c\ub294 \uac83\uc774\ub2e4. \uc870\uae08 \uc560\ub9e4\ud558\uc9c0\ub9cc \uacb0\ub860\uc744 \uc870\uae08 \ub0b4\uc790\uba74 \uc5bc\ub9ac\ud14d \uac80\uc0ac\ub9cc\uc73c\ub85c\ub294 \ub300\uc7a5\uc554\/\uc6a9\uc885\/\uc120\uc885\uc744 \ud655\uc9c4\ud560 \uc218 \uc5c6\uc9c0\ub9cc \ubc1c\uc0dd\uc758 \uac00\ub2a5\uc131\uc744 \uc54c\ub824 \uc904 \uc218 \uc788\ub294 \ubcf4\uc870\uac80\uc9c4 \uc7a5\uce58\ub77c\uace0 \ud560 \uc218 \uc788\ub2e4. <\/p>\n\n\n\n
NED\uc5d0\uc11c \uac80\ucd9c\ub418\ub294 \uba54\ud2f8\ud654 \uc2e0\ub370\uce78-2\ub97c \uace0\ub824\ud558\uc5ec \uba54\ud2f8\ud654 \uc2e0\ub370\uce78-2 \uac80\ucd9c \uc790\uccb4\ub97c \uc591\uc131\uc73c\ub85c \ud310\ub2e8\ud558\uc9c0\ub294 \uc54a\ub294\ub2e4. \ub0b4 \uac80\uc9c4 \uacb0\uacfc 2\uac1c\ub144\ub3c4\ub97c \ube44\uad50 \ud558\uba74 ’22\ub144\uc5d0\ub3c4 \uc18c\ub7c9 \uac80\ucd9c \ub41c \uac83\uc744 \uc54c \uc218 \uc788\ub2e4. \uadf8\ub7f0\ub370 ’23\ub144\uc740 \uae30\uc900\uce58\ub97c \uc0b4\uc9dd \ub118\uc5b4 \uc591\uc131 \ud310\uc815\uc774 \ub418\uc5c8\ub2e4\ub294 \uac83\uc774\ub2e4. \uadf8\ub807\ub2e4\uba74, \uc5b4\ub290 \uc815\ub3c4 \uc591\uc758 \uba54\ud2f8\ud654 \uc2e0\ub370\uce78-2\uac00 \uac80\ucd9c\uc774 \ub418\uba74 \uc591\uc131\uc774\ub77c\uace0 \ud560 \uc218 \uc788\ub294\uac00? \uc55e\uc5d0\uc11c \ubcf8 Fig.3\uc758 CRC \ubc15\uc2a4 Plot\uc758 \ucd5c\ud558\ub2e8\uc77c \uc218\ub3c4 \uc788\uace0, \uc9c0\ub178\ubbf8\ud2b8\ub9ad\uc5d0\uc11c \uccb4\ud5d8\uc801\uc73c\ub85c \uc815\ud55c \uc218\uce58\uc77c \uc218 \uc788\ub2e4. <\/p>\n\n\n\n
\uc704\uc591\uc131\uacfc \uc704\uc74c\uc131\uc740 Trade-off \uad00\uacc4\uc5d0 \uc788\ub2e4. \uadf8\ub807\uae30 \ub54c\ubb38\uc5d0 NED\uc5d0\uc11c \ubc1c\uc0dd\ud558\ub294 \uba54\ud2f8\ud654 \uc2e0\ub370\uce78-2\uc640 CRC\uc758 \uba54\ud2f8\ud654 \uc2e0\ub370\uce78-2\ub97c \ud655\uc2e4\ud788 \uad6c\ubcc4\ud558\uac70\ub098(\uac00\ub2a5\ud55c\uc9c0\ub294 \ubb38\uc678\ud55c\uc73c\ub85c\uc368 \uc54c \uc218 \uc5c6\uc9c0\ub9cc) \ub2e4\ub978 \ucd94\uac00 \uc9c0\ud45c\ub97c \ud1b5\ud574\uc11c \uc591\/\uc74c\uc131 \ud310\ub2e8\uc744 \ud574\uc57c \ud55c\ub2e4\uace0 \uc0dd\uac01\ud55c\ub2e4.(\ub2e4\ubd84\ud788 \uac1c\uc778\uc801 \uc758\uacac\uc784) \uc774 \ubd80\ubd84\uc774 \uc815\uad50\ud558\uc9c0 \uc54a\ub2e4\uba74 \uc704\uc591\uc131 \ubb38\uc81c\ub294 \uc544\ub9c8\ub3c4 \uacc4\uc18d \uc0dd\uae30\uc9c0 \uc54a\uc744\uae4c\ub77c\uace0 \ucd94\uce21\ud574 \ubcf8\ub2e4.<\/p>\n\n\n\n
\uc9c0\uae08\uae4c\uc9c0 \ub17c\ubb38\uc73c\ub85c \uba54\ud2f8\ud654 \uc2e0\ub370\uce78-2\uc640 \uac80\ucd9c\uc5d0 \ub300\ud55c \uc758\ubbf8\ub97c \ub17c\ubb38\uc73c\ub85c \ucd94\uce21\ud574\ubd24\ub2e4. \ubcf8\uc778\uc740 \uc758\ud559\uc801 \uc9c0\uc2dd \uc5c6\uc774 \ub17c\ubb38\uc758 \uc22b\uc790\ub9cc\uc73c\ub85c \ud310\ub2e8\ud55c \uac83\uc774\uae30 \ub54c\ubb38\uc5d0 \uc798\ubabb\ub41c \ud574\uc11d\uc774 \uc788\uc744 \uc218 \uc788\uc73c\ub2c8 \uc774\uc810 \ubc18\ub4dc\uc2dc \uace0\ub824\ud558\uace0 \uc77d\uace0 \ud310\ub2e8\ud558\uae30 \ubc14\ub780\ub2e4.<\/p>\n\n\n\n
\uac1c\uc778\uc801\uc778 \uc0dd\uac01\uc740 \uc5bc\ub9ac\ud14d\uc758 \uae30\uc220\uc801\uc778 \uc7a5\uc810\uc740 \uba54\ud2f8\ud654 \uc2e0\ub370\uce78-2\uc758 \ud2b9\uc131\uc744 \ubc1d\ud600\ub0b4\uace0 \uc774\ub97c \uac80\uccb4\ub85c \ubd80\ud130 \uac80\ucd9c\ud574 \ub0b4\ub294 \uae30\uc220\uc774\ub2e4. \ud648\ud398\uc774\uc9c0\uc758 \ubb38\uad6c\ub97c \ubcf4\uba74 \uc54c \uc218 \uc788\ub2e4. <\/p>\n\n\n\n
\n
‘\uc5bc\ub9ac\ud14d\u00ae \ub300\uc7a5\uc554\uac80\uc0ac\ub294 \uccb4\uc678\uc9c4\ub2e8\uc6a9 \uc758\ub8cc\uae30\uae30 EarlyTect Colon Cancer (\uc81c\ud5c8 18-593\ud638)\ub97c \uc0ac\uc6a9\ud558\uc5ec, \uc0ac\ub78c \ubd84\ubcc0\uc5d0\uc11c \ucd94\ucd9c\ud55c DNA\uc5d0\uc11c \uc2e0\ub370\uce78-2(SDC2) \uc720\uc804\uc790\uc758 \uba54\ud2f8\ud654(methylation)\ub97c \uc2e4\uc2dc\uac04 \uc911\ud569\ud6a8\uc18c \uc5f0\uc1c4\ubc18\uc751(real-time PCR)\uc73c\ub85c \uc815\uc131\ud558\uc5ec \ub300\uc7a5\uc554 \uc9c4\ub2e8\uc5d0 \ubcf4\uc870\uc801\uc73c\ub85c \uc0ac\uc6a9\ud558\ub294 \ubd84\uc790\uc9c4\ub2e8 \uac80\uc0ac\uc785\ub2c8\ub2e4.’<\/p>\n(\ucd9c\ucc98:\uc5bc\ub9ac\ud14d \ud648\ud398\uc774\uc9c0 – <\/strong>Link<\/a>)<\/strong><\/cite><\/blockquote>\n\n\n\n
\uae00\uc774 \uc810\uc810 \uc0b0\uc73c\ub85c \uac00\ub294 \uac83 \uac19\uc544 \ub9c8\ubb34\ub9ac\ub97c \ud574\uc57c\uaca0\ub2e4… \u3160.\u3160<\/p>\n\n\n\n
\uc5bc\ub9ac\ud14d\uc740 \ub300\uc7a5\uc554\/\uc6a9\uc885\/\uc120\uc885\uc5d0 \ub300\ud574 \ub300\uc7a5 \ub0b4\uc2dc\uacbd \uc2dc\ud589 \uc804 \uc120\uc81c\uc801\uc73c\ub85c \uc874\uc7ac \uac00\ub2a5\uc131 \ud655\uc778\ud560 \uc218 \uc788\ub294 \uc88b\uc740 \uc9c4\ub2e8\ubc29\ubc95\uc774\ub77c\uace0 \uc0dd\uac01\ud55c\ub2e4. \ub610\ub294 \ub300\uc7a5 \ub0b4\uc2dc\uacbd \uc2dc\ud589\uc5d0 \ud070 \uc5b4\ub824\uc6c0\uc744 \uacaa\uc744 \uc218 \uc788\ub294 \uc0ac\ub78c\ub4e4\uc740 \ub300\uccb4\uc801\uc73c\ub85c \uc2dc\ud589\ud560 \uc218 \uc788\ub294 \ubc29\ubc95\uc774\ub77c\uace0 \uc0dd\uac01\ud55c\ub2e4.<\/p>\n\n\n\n
\uc5bc\ub9ac\ud14d \ub300\uc7a5\uc554 \ubcf4\uc870\uc9c4\ub2e8 \uac80\uc0ac\uc758 \ub9e4\uce74\ub2c8\uc998\/\uc54c\uace0\ub9ac\uc998\uc740 \uc774\ub807\ub2e4.<\/p>\n\n\n\n
1) \uba54\ud2f8\ud654 \uc2e0\ub370\uce78-2 \ubb3c\uc9c8\uc740 \ub300\uc7a5\uc554\/\uc6a9\uc885\/\uc120\uc885\uc5d0\uc11c \ub2e4\ub7c9 \uac80\ucd9c\ub418\ub294 \ubb3c\uc9c8\uc774\ub2e4. 2) \uac80\uc9c4 \ub300\uc0c1\uc790\uc758 \ubd84\ubcc0(Stool)\uc5d0\uc11c \uba54\ud2f8\ud654 \uc2e0\ub370\uce78-2 \ubb3c\uc9c8\uc744 \uac80\ucd9c\ud558\ub294 \uac80\uc0ac(PCR)\ub97c \uc2dc\ud589\ud55c\ub2e4. 3) \uc77c\uc815 \uc218\uc900 \uc774\uc0c1\uc758 \uba54\ud2f8\ud654 \uc2e0\ub370\uce78-2\uac00 \uac80\ucd9c\uc774 \ub418\uba74 \ub300\uc7a5\uc554\/\uc6a9\uc911\/\uc120\uc885\uc774 \uc788\uc744 \uac00\ub2a5\uc131\uc774 \uc788\uc73c\ubbc0\ub85c \ub300\uc7a5 \ub0b4\uc2dc\uacbd \ub4f1 \uc815\ubc00 \uac80\uc0ac\ub97c \ud1b5\ud574\uc11c \ud655\uc778\ud55c\ub2e4.<\/p>\n\n\n\n
\uc989, \uac80\uc0ac \uacb0\uacfc \uc591\uc131\/\uc74c\uc131\uc740 \ubcf4\uc870 \uc9c0\ud45c\ub77c\ub294 \uc774\uc57c\uae30 \uc774\ub2e4. \uadf8\ub798\uc11c \uc591\uc131 \ud310\uc815\uc2dc \ube60\ub974\uac8c \ub300\uc7a5\ub0b4\uc2dc\uacbd\uc744 \ud1b5\ud574\uc11c \uba85\ud655\ud788 \ud655\uc778\ud574 \ubcf4\uc2dc\uae38 \ubc14\ub780\ub2e4. \ub300\uc7a5\uc554\uc740 \ub2e4\ub978 \uc5ec\ub290\uc554\uacfc \ub2e4\ub974\uac8c \uc9c4\ud589 \uc18d\ub3c4\uac00 \ub2a6\uae30 \ub54c\ubb38\uc5d0 \ub9e4\ub144 \uac80\uc0ac\ub97c \uc9c4\ud589\ud55c\ub2e4\uba74 \uc870\uae30\uc5d0 \ubc1c\uacac\ud558\uace0 \uce58\ub8cc\ud560 \uc218 \uc788\ub2e4\uace0 \ud55c\ub2e4.<\/p>\n\n\n\n
\uc9e7\uc740 \uc2dd\uacac\uc774\uc9c0\ub9cc \ubd84\uc11d\ud55c \uacb0\uacfc \uc5bc\ub9ac\ud14d \ub300\uc7a5\uc554 \ubcf4\uc870\uc9c4\ub2e8 \uac80\uc0ac\uc758 \uc7a5\/\ub2e8\uc810\uc744 \uc815\ub9ac\ud574 \ubcf4\uc558\ub2e4.<\/p>\n\n\n\n
\uc7a5\uc810<\/td>\ub2e8\uc810<\/td><\/tr>
– \ub300\uc7a5 \ub0b4\uc2dc\uacbd\uc744 \uc704\ud55c \uc0ac\uc804 \uc900\ube44\uac00 \ud544\uc694 \uc5c6\ub2e4.(\uc74c\uc2dd \uc870\uc808\uacfc  \uc7a5\uc138\ucc99)
– \ub0b4\uc2dc\uacbd \uc9c4\ud589\uc5d0 \ub530\ub978 \ubd88\ud3b8\ud568\uc774 \uc5c6\ub2e4. \uc218\uba74\ub0b4\uc2dc\uacbd \ubd88\uac00\ud55c \uac80\uc9c4\uc790\ub3c4 \uac00\ub2a5
– \ub9e4\ub144 \uc885\ud569\uac74\uac10\uac80\uc9c4\uc2dc \uc9c4\ud589\ud558\uc5ec\ub3c4 \uc2ec\uc801\/\uc2e0\uccb4\uc801 \ubd80\ub2f4\uac10\uc774 \ub9e4\uc6b0 \uc801\ub2e4.<\/td>		– \ud310\uc815 \uacb0\uacfc\uac00 \ub300\uc7a5\uc554\/\uc6a9\uc885\/\uc120\uc885 \uc874\uc7ac \uc5ec\ubd80\uc5d0 \ub300\ud55c \uba85\ud655\ud55c \ub2f5\uc774 \uc544\ub2d0 \uc218 \uc788\ub2e4.
– \uc591\uc131 \ud310\uc815\uc774 \ub098\uc62c \uacbd\uc6b0 \ub300\uc7a5 \ub0b4\uc2dc\uacbd\uc744 \uc9c4\ud589\ud574\uc57c \ud55c\ub2e4.
– \uc74c\uc131 \ud310\uc815\uc5d0\ub3c4 \uc704\uc74c\uc131(9.8%)\uc774 \uc874\uc7ac \ud558\uae30 \ub54c\ubb38\uc5d0 \uc815\uc0c1 \uc0c1\ud0dc\ub97c \ub2f4\ubcf4\ud560 \uc218\uc5c6\ub2e4.<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n
\ub098\uc5d0\uac8c \ub2e4\uc2dc \uc5bc\ub9ac\ud14d \uac80\uc0ac\ub97c \ud560 \uac83\uc774\ub0d0\uace0 \ubb3b\ub294\ub2e4\uba74. \ub098\ub294 \uc218\uba74 \ub0b4\uc2dc\uacbd \ud558\uba74\uc11c \ub300\uc7a5 \ub0b4\uc2dc\uacbd\uc744 \ud568\uaed8 \ubc1b\ub294\uac8c \ub354 \uc720\uc6a9\ud558\ub2e4\uace0 \uc0dd\uac01\ud55c\ub2e4. \uc704\uc591\uc131\uc758 \uac00\ub2a5\uc131\uc774 \ub0ae\ub2e4\uace0 \ud558\ub354\ub77c\ub3c4 \ud55c \ubc88 \uacbd\ud5d8\ud574 \ubcf8 \uc785\uc7a5\uc5d0\uc11c \uc7a5\uc138\ucc99 \uc790\uccb4\uc5d0 \ucee4\ub2e4\ub780 \uc5b4\ub824\uc6c0\uc774 \uc5c6\uae30 \ub54c\ubb38\uc5d0 \uacb0\uacfc \ud6c4 \ubd88\uc548\ud55c \uae30\uac04\uc744 \uac00\uc9c0\ub294 \uac83\ubcf4\ub2e4\ub294 \uacb0\uacfc\ub97c \ube60\ub974\uace0 \uc721\uc548\uc73c\ub85c \ud655\uc778\ud560 \uc218 \uc788\ub294 \ub300\uc7a5\ub0b4\uc2dc\uacbd\uc744 \uc120\ud0dd\ud558\uaca0\ub2e4.<\/p>\n\n\n\n
\uadf8\ub807\ub2e4\uba74 \uc5bc\ub9ac\ud14d\uc774 \ubd88\ud544\uc694\ud558\uace0 \ubd80\uc815\ud655\ud55c \uac80\uc0ac\ub0d0\uace0 \ubb3b\ub294\ub2e4\uba74 \uadf8\uac83\uc740 \uc544\ub2c8\ub77c\uace0 \uc0dd\uac01\ud55c\ub2e4. 5\ub144 \uc8fc\uae30\ub85c \ub300\uc7a5\ub0b4\uc2dc\uacbd\uc744 \uc9c4\ud589\ud558\uace0 \uae30\ud0c0 \ub144\ub3c4\uc5d0\ub294 \uc5bc\ub9ac\ud14d\uc744 \uc9c4\ud589\ud55c\ub2e4\uba74 \uc88b\uc740 \ubc29\ubc95\uc774\ub77c\uace0 \uc0dd\uac01\ud55c\ub2e4. \ud1b5\uc0c1 5\ub144\uc774 \uc548\uc804\ud558\ub2e4\uace0 \ud558\uc9c0\ub9cc \uc0ac\ub78c\uc758 \uac74\uac15\uc774\ub780\uac8c \uadf8\ub807\uac8c \uc218\uce58\uc801\uc73c\ub85c \ub2f4\ubcf4\ub418\ub294 \uac83\uc774 \uc544\ub2c8\uae30 \ub54c\ubb38\uc5d0 \uc120\uc81c\uc801\uc778 \uac80\uc0ac\ub85c \uc774\uc0c1 \uc720\ubb34\ub97c \ud310\ub2e8\ud558\uace0 \ud544\uc694\uc2dc \ub300\uc7a5 \ub0b4\uc2dc\uacbd\uc73c\ub85c \uac80\uc0ac \ud558\uc5ec \uc870\uce58\ub97c \ud558\uba74 \ub2e4\uc74c 5\ub144\uac04\uc740 \uc870\uae08 \uc26c\uc6b4 \uac80\uc0ac\ub97c \ud560 \uc218 \uc788\uc744 \uac83\uc774\ub2e4.<\/p>\n\n\n\n
\uadf8\ub9ac\uace0 \uc5ec\ub7ec \uc774\uc720\ub85c \uc218\uba74 \ub0b4\uc2dc\uacbd\uc774 \uc5b4\ub824\uc6b0\uc2e0 \ubd84\ub4e4\uc5d0\uac8c\ub294 \ube44\uc218\uba74 \ub300\uc7a5 \ub0b4\uc2dc\uacbd\uc774\ub77c\ub294 \uc5b4\ub9c8 \uc5b4\ub9c8\ud55c \uace0\ud1b5\uc774 \uc544\ub2cc \ub2e4\ub978 \ubc29\ubc95\uc774 \uc788\ub2e4\ub294 \uac83 \uc790\uccb4\ub3c4 \uc88b\uc740 \ud604\uc0c1\uc774\ub77c \uc0dd\uac01\ud55c\ub2e4.<\/p>\n\n\n\n
\uac00\uc7a5 \uc911\uc694\ud55c\uac74 \uac74\uac15\uc740 \uc790\uc2e0\ud558\uac70\ub098 \ub2f4\ubcf4\ud560 \uc218 \uc5c6\ub294 \uac83\uc774\uae30 \ub54c\ubb38\uc5d0 \ubcd1\uc744 \uc870\uae30\uc5d0 \ubc1c\uacac\ud558\uace0 \ube60\ub974\uac8c \uce58\ub8cc\ud558\ub294\uac8c \uac00\uc7a5 \uc911\uc694\ud558\ub2e4. \uc78a\uc9c0 \ub9d0\uace0, \ub2a6\uc9c0 \ub9d0\uace0 \uaf2d \uac74\uac15\uac80\uc9c4 \ubc1b\uae30\ub97c \ubc14\ub77c\uba70… \uc7ac\ubbf8\ub09c \ubc08 \ud558\ub098 \ucd94\uac00 \ud558\uba74\uc11c \ub9c8\uce58\ub3c4\ub85d \ud55c\ub2e4.<\/p>\n\n\n
\n
\"\"
\ucd9c\ucc98: https:\/\/twitter.com\/textfiles\/status\/1429455146237501443<\/figcaption><\/figure>\n<\/div>\n\n\n
\uc704 \ub0b4\uc6a9 \uc911 \uc218\uc815\uc774 \ud544\uc694\ud558\uac70\ub098 \uc798\ubabb\ub41c \ub0b4\uc6a9\uc774 \uc788\ub2e4\uba74 \ub313\uae00\ub85c \uc54c\ub824\uc8fc\uc138\uc694. \ud655\uc778 \ud6c4 \uc218\uc815\ud558\ub3c4\ub85d \ud558\uaca0\uc2b5\ub2c8\ub2e4. (\ub313\uae00\uc740 \uc2a4\ud3a8\ubc29\uc9c0\ub85c \ubc14\ub85c \ub4f1\ub85d\uc774 \uc548\ub418\uace0 \uc81c\uac00 \ud655\uc778 \ud6c4 \ub4f1\ub85d \ub429\ub2c8\ub2e4.)<\/pre>\n","protected":false},"excerpt":{"rendered":"
\ubcf8 \ud3ec\uc2a4\ud305\uc740 \uc5bc\ub9ac\ud14d\uc758 \uac80\uc0ac \uacb0\uacfc\ub098, \uac80\uc0ac \uc790\uccb4\uc5d0 \uc774\uc288\ub97c \uc81c\uae30 \ud558\uae30 \uc704\ud55c \ud3ec\uc2a4\ud305\uc774 \uc544\ub2d9\ub2c8\ub2e4. \uc5bc\ub9ac\ud14d \uc790\uccb4\uc5d0 \ub300\ud55c \uc815\ubcf4\uac00 \uc778\ud130\ub137 \uc0c1\uc5d0 \ub9ce\uc9c0 \uc54a\uace0, \uc81c\uac00 \uacaa\uc740 \uacbd\ud5d8\uacfc \uadf8 \uacfc\uc815\uc5d0\uc11c \uc624\ud574 \ud560 \uc218 \uc788\ub294\uc77d\uc5b4 \ubcfc\uae4c?\uc5bc\ub9ac\ud14d \uacb0\uacfc \uc704\uc591\uc131(False-Positive) \uc18c\ub3d9 \ud6c4\uae30<\/span><\/a><\/span><\/p>\n","protected":false},"author":1,"featured_media":670,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[35,3],"tags":[259,245,248,251,241,254,256,253,255,250,239,252,247,260,246,258,249],"class_list":["post-712","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-35","category-review_root","tag-stool","tag-245","tag-248","tag-251","tag-241","tag---2","tag-256","tag-253","tag-255","tag-250","tag-239","tag-252","tag-247","tag-260","tag-246","tag-258","tag-249"],"_links":{"self":[{"href":"http:\/\/kyunam.com\/index.php?rest_route=\/wp\/v2\/posts\/712","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/kyunam.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/kyunam.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/kyunam.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/kyunam.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=712"}],"version-history":[{"count":2,"href":"http:\/\/kyunam.com\/index.php?rest_route=\/wp\/v2\/posts\/712\/revisions"}],"predecessor-version":[{"id":715,"href":"http:\/\/kyunam.com\/index.php?rest_route=\/wp\/v2\/posts\/712\/revisions\/715"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/kyunam.com\/index.php?rest_route=\/wp\/v2\/media\/670"}],"wp:attachment":[{"href":"http:\/\/kyunam.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=712"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/kyunam.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=712"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/kyunam.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=712"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}